The canton Vesoul-2 has 13 communes.
| Code | Name | Population ▼ |
|---|---|---|
| 70550 | Vesoul | 15 078 |
| 70378 | Navenne | 1 579 |
| 70261 | Frotey-lès-Vesoul | 1 354 |
| 70433 | Quincey | 1 338 |
| 70163 | Colombier | 434 |
| 70358 | Montcey | 264 |
| 70559 | Villeparois | 194 |
| 70179 | Coulevon | 176 |
| 70558 | La Villeneuve-Bellenoye-et-la-Maize | 160 |
| 70522 | Varogne | 155 |
| 70166 | Comberjon | 141 |
| 70534 | Vellefrie | 122 |
| 70569 | Vilory | 68 |